真菌遺傳研究室 — _英文版

• Editor:: Applied and Environmental Microbiology (2012–2017)
• Editor: Physiological and Molecular Plant Pathology
  (2014–2016)
• Editor: Austin Journal of Plant Biology (2014–present)
• Editor: Journal of Fungi (2014–present)
• Editor: Advances in Biology (2013–present)
• Editor: The Scientific World Journal-Molecular Biology
  (2013–present)
• Associate Editor, Molecular Plant-Microbe Interactions
  (2007–2009)

1. Fungal Pathogenicity
2. Plant-Fungal Interactions
3. Fungal toxins; Plant Hormones
4. Secondary Metabolites in Fungi
5. Signal Transductions in Fungi

My research centers on the understanding molecular and genetic mechanisms
involved in fungal pathogenicity or virulence. Current projects are aimed at the
investigation of the signaling pathways leading to ROS detoxification, cellular
resistance to osmotic stress and multidrug, fungicide sensitivity, spore
formation, iron acquisition and pathogenicity of the tangerine pathotype of
Alternaria alternata. Research is also concentrated on the investigation of
the biosynthetic gene clusters and pathogenicity roles of cercosporin and
elsinochrome toxins produced by Cercospora nicotianae and Esinoë
fawcettii, respectively.

上學期 :
大四專題討論(一)
碩一真菌遺傳學特論(全)
碩一當代植物病理學專論
下學期 :
碩一真菌遺傳學特論(全)
碩二真菌分子遺傳技術
碩博班專題討論　

1. Lin, T.-C., Hsieh, T.-Y., Lin, C.-L., Chung, W.-C., Chung, K.-R., and Huang,
   J.-W. 2016. Pathogenic fungal proteins-induced resistance and its effects on
   vegetable diseases. Journal of Agricultural Science (revision)
2. Chen, L.-H., Tsai, H.-C., and Chung, K.-R.* 2016. A major facilitator
   superfamily transporter-mediated resistance to oxidative stress and fungicides
   requires Yap1, Skn7, and MAP kinases in the citrus fungal pathogen Alternaria
   alternata. PLoS One (in press)
3. Wang, M., Sun, X., Yu, D., Xu, J., Chung, K.-R., Li, H. 2016. Genomic and
   transcriptomic analyses of the tangerine pathotype of Alternaria alternata in
   response to oxidative stress. Scientific Reports 6:32437 DOI: 10.1038/srep32437
4. Yang, S.L, Yu, P.-L., and Chung, K.-R.* 2016. The glutathione peroxidase–mediated
   ROS resistance, fungicide sensitivity and cell wall construction in the citrus
   fungal pathogen Alternaria alternata. Environmental Microbiology 18: 923-935.
5. Yu, P.-L., L.-H. Chen, Chung K.-R.* 2016. How the pathogenic fungus
   Alternaria
   alternata copes with stress via the response regulators SSK1 and SHO1. PLoS One
   11(2): e0149153. Doi:10.137/journal.pone.0149153
6. Ma, H., Sun, X., Wang, M., Gai, Y., Chung, K.-R., and Li, H. 2016. The citrus
   postharvest pathogen Penicillium digitatum depends on the PdMpkB kinase for
   developmental and virulent functions. International J Food Microbiology 236:
   167–176.
7. Hsieh, T.-Y., Lin, T.-C., Lin, C.-L., Chung, K.-R., and Huang, J.-W. 2016.
   Reduction of Rhizoctonia damping-off in Chinese cabbage seedlings by fungal
   protein activators. Journal of Plant Medicine 58: 1–8.
8. Wang, W., Wang, M., Wang, J., Zhu, C., Chung, K.-R., and Li, H. 2016. Adenylyl
   cyclase is required for cAMP production, growth, conidial germination, and
   virulence in the citrus green mold pathogen Penicillium digitatum.
   Microbiological Research 192: 11-20.
9. Chang, S.-C., Deng, W.-L., Huang, H.-C., Chung, K.-R., and Tzeng, K.-C. 2016.
   Differential expression of pectolytic enzyme genes in Xanthomonas citri subsp.
   citri and demonstration that pectate lyase Pel3 is required for the formation of
   citrus canker. Microbiological Research 192: 1-10.
10. Chen, P.-S., Peng, Y.-H., Chung, W.-C., Chung, K.-R., Huang, H.-C., and Huang,
    J.-W. 2016. Inhibition of Penicillium digitatum and citrus green mold by
    volatile compounds produced by Enterobacter cloacae. J. Plant Pathol. Microbiol.
    7: 339. doi:10.4172/2157-7471.1000339
11. Chou, C.-M., F.-Y. Yu, P.-L. Yu, R. M. Bostock, K.-R. Chung, C.-Y. Chen, J.-W.
    Huang, M.-H. Lee. 2015. Differential expression of five endopolygalacturonase
    genes and demonstration that MgPG1 overexpression diminishes virulence in the
    brown rot pathogen Monilina fructicola. PLoS One 10(6): e0132012. (June 29,
    2015)
12. Chung, K.-R. 2014. Reactive oxygen species in the citrus fungal pathogen
    Alternaria alternata: The roles of NADPH oxidase. Physiological and Molecular
    Plant Pathology 88: 10-17. (invited review)
13. Lin, C.-H., and Chung K.-R.* 2014. Interactions of MAP kinases, histidine kinase
    and YAP1 in the citrus fungal pathogen Alternaria alternata. Plant Pathology
    Bulletin 23: 307-315.
14. Chung, K.-R., and M.-H. Lee. 2014. Split marker-mediated transformation and
    targeted gene disruption in filamentous fungi. In: M. van den Berg and K.
    Maruthachalam (eds.) Genetic Transformation System in Fungi. Springer Publishes,
    NY (in press) (invited contribution)
15. Tsai, H.-C., and K.-R. Chung. 2014. Calcineurin phosphatase and phospholipase C
    are required for developmental and pathological functions in the citrus fungal
    pathogen Alternaria alternata. Microbiology 160: 1453-1465.
16. Chen, L.-H., S.L. Yang and K.-R. Chung.
    2014. Resistance to oxidative stress via regulating siderophore-mediated
    iron-acquisition by the citrus fungal pathogen Alternaria
    alternata. Microbiology 160: 970-979.
17. Kim, H.-K., N. Khorram, S. L. Yang, K.-R. Chung and T. A. Doherty. 2013.
    Impaired induction of allergic lung inflammation by Alternaria alternata mutant
    MAPK homologue FUS3. Experimental Lung Research 39(9): 399-409.
18. Daub, M. E., S. Herrero and K.-R. Chung. 2013. Reactive oxygen species in plant
    pathogenesis: the role of perylenequinone photosensitizers. Antioxidants and
    Redox Signaling 19: 970-989. (invited review)
19. Chung, K.-R. 2013. Mitogen-activated protein kinase signaling pathways of the
    tangerine pathotype of Alternaria alternata. MAP Kinase 2013; 2:e4
    doi:10.4081/mk.2013.e4 (invited review)
20. Yang, S. L., and K.-R. Chung. 2013. Similar and distinct roles of NADPH oxidase
    components in the tangerine pathotype of Alternaria alternata. Molecular Plant
    Pathology 14: 543-556.
21. Chen, L.-H., C.-H. Lin, and K.-R. Chung. 2013. A nonribosomal peptide synthetase
    mediates siderophore production and virulence in the citrus fungal pathogen
    Alternaria alternata. Molecular Plant Pathology 14: 497-505.
22. Chiu, C.-M., C.-M. Chou, F.-Y. Yu, S.-M. Pan, P.-L. You, R. M. Bostock,
    K.-R.
    Chung and M.-H. Lee. 2013. Redox status-mediated regulation of gene expression
    and fungal virulence in the brown rot pathogen Monilina fructicola. Plant
    Pathology 62: 809-819.
23. Tsai, H.-C., S. L. Yang, and K.-R. Chung. 2013. Cyclic AMP-dependent protein
    kinase A negatively regulates conidia formation by the tangerine pathotype of
    Alternaria alternata. World Journal of Microbiology and Biotechnology 29:
    289-300.
24. Chung, K.-R. 2012. Toxicity and biosynthesis of elsinochrome phytotoxin. Plant
    Pathology Bulletin 21: 221-229. (invited review)
25. Chung, K.-R. 2012. Stress response and pathogenicity of the necrotrophic fungal
    pathogen Alternaria alternata. Scientifica 2012, 635431
    http://dx.doi.org/10.6064/2012/635431 (invited review)
26. You, B.-J., Chang, W.-T., Chung, K.-R., Kuo, Y.-H., Yang, C.-S., Tien, N.,
    Hsieh, H.-C., Lai, C.-C. & Lee, H.-Z., 2012. Effect of solid-medium coupled with
    reactive oxygen species on ganoderic acid biosynthesis and MAP kinase
    phosphorylation in Ganoderma lucidum, Food Research International 49: 634-640.
27. Chen, L.-H., C.-H. Lin, and K.-R. Chung. 2012. Roles for SKN7 response regulator
    in stress resistance, conidiation and virulence in the citrus pathogen
    Alternaria alternata. Fungal Genetics and Biology 49: 802-813.
28. Chung, K.-R. 2012. The non-host selective toxin cercosporin produced by
    Cercospora species. Plant Pathology Bulletin 21: 199-212. (invited review)
29. You, B.-J., H.-Z. Lee, K.-R. Chung, M.-H. Lee, M.-J. Huang, N. Tein, C.-W. Chen,
    and Y.-H. Kuo. 2012. Enhanced production of ganoderic acids and cytotoxicity by
    Ganoderma lucidum using solid-medium culture. Bioscience, Biotechnology, and
    Biochemistry 76: 1529-1534.
30. Yang, S. L., and K.-R. Chung. 2012. The NADPH oxidase-mediated production of
    hydrogen peroxide (H2O2) and resistance to oxidative stress in the necrotrophic
    pathogen Alternaria alternata of citrus. Molecular Plant Pathology 13: 900-914.
31. Graham, J.H., G.C. Colburn, K.R. Chung, and J. Cubero. 2012. Protection of
    citrus roots against infection by Phytophthora spp. by hypovirulent P.
    nicotianae is not related to induction of systemic acquired resistance. Plant
    and Soil 358: 39-49.
32. Liao, C.-Y., M.-Y. Chen, Y.-K. Chen, Z.-M. Sheu, K.-C. Kuo, P.-F. Chang, K.-R.
    Chung, and M.-H. Lee. 2012. Characterization of three Colletotrichum acutatum
    isolates from Capsicum spp. European Journal of Plant Pathology 133: 599–608.
33. Chen, P.-S., L.-Y. Wang, Y.-J. Chen, K.-C. Tzeng, K.-R. Chung, and M.-H. Lee.
    2012. Understanding cellular defence in kumquat and calamondin to citrus canker
    caused by Xanthomonas citri subsp. citri. Physiological and Molecular Plant
    Pathology 79: 1–12.
34. Liao, C.-Y., M.-Y. Chen, Y.-K. Chen, K.-C. Kuo, K.-R. Chung, and M.-H. Lee.
    2012. Formation of highly branched hyphae by Colletotrichum acutatum within the
    fruit cuticles of Capsicum spp. Plant Pathology 61: 262–270.
35. Yago, J.I. and K.-R. Chung. 2011. First report of twig blight disease of citrus
    caused by Haematonectria haematococca in Philippines. Plant Disease 95 (12):
    1590
36. Lee, M.-H., S.-M. Pan, T.-W. Ng, L.-Y. Wang, K.-R. Chung. 2011. Mutations of
    beta tubulin codon 198 or 200 indicate resistance to thiabendazole among
    isolates of Penicillium digitatum collected from citrus in Taiwan. International
    Journal of Food Microbiology 150: 157–163.
37. Wang, N., S. L. Yang, C.-H., Lin, and K.-R. Chung. 2011. Gene inactivation in
    the citrus pathogenic fungus Alternaria alternata defect at the Ku70 gene
    associated with non-homologous end joining. World Journal of Microbiology and
    Biotechnology 27: 1817–1826.
38. Chung, K.-R. 2011. Elsinoë fawcettii and
    Elsinoë australis: the fungal pathogens
    causing citrus scab. Molecular Plant Pathology 12: 123–135.
39. Yago, J.I., C.-H. Lin, and K.-R. Chung. 2011. The SLT2 MAP kinase-mediated
    signalling pathway governs conidiation, morphogenesis, fungal virulence, and
    production of toxin and melanin in the tangerine pathotype of Alternaria
    alternata. Molecular Plant Pathology 12: 653–665.
40. Lin, C.-H., S. L. Yang, and K.-R. Chung. 2011. Cellular responses required for
    oxidative stress tolerance, colonization and lesion formation by the
    necrotrophic fungus Alternaria alternata in citrus. Current Microbiology 62:
    807–815.
41. Lin, C.-H., and K.-R. Chung. 2010. Specialized and shared functions of the
    histidine kinase and HOG1 MAP kinase-mediated signaling pathways in the
    filamentous fungus Alternaria alternata of citrus. Fungal Genetics and Biology
    47: 818–827.
42. Lin, C.-H., S. L. Yang, N. Wang, and K.-R. Chung. 2010. The FUS3 MAPK signaling
    pathway of the citrus pathogen Alternaria alternata acts independently and
    cooperatively with the fungal redox-responsive AP1 regulator for diverse
    developmental, physiological and pathogenic functions. Fungal Genetics and
    Biology 47: 381–391.
43. Achor, D.S., E. Etxeberris, N. Wang, S.Y. Folimonova,
    K.R. Chung and L.G. Albrigo. 2010. Sequence of anatomical symptom observations in citrus affected
    with Huanglongbing disease. Plant Pathology J. 9: 56-64.
44. Wang, N., C.-H. Lin, and K.-R. Chung. 2010. A Gα subunit gene is essential for
    conidiation and potassium efflux but dispensable for pathogenicity of Alternaria
    alternata in citrus. Current Genetics 56: 43–51.
45. Yang, S. L., and K.-R. Chung. 2010. Transcriptional regulation of elsinochrome
    phytotoxin biosynthesis by an EfSTE12 activator from the citrus scab pathogen
    Elsinoë fawcettii. Fungal Biology 114: 64–73.
46. Weiland, J. J., K.-R. Chung, and J. C. Suttle. 2010. The role of cercosporin in
    the virulence of Cercospora spp. to plant hosts. In: Cercospora Leaf Spot of
    Sugar Beet and Related Species. Ed. Lartey et al., pp. 109–117, APS Press, St.
    Paul, MN
47. Yang, S.-L., Lin, C.-H., and K.-R. Chung. 2009. Coordinate control of oxidative
    stress tolerance, vegetative growth, and fungal pathogenicity via the
    AP1-mediated pathway in the rough lemon pathotype of Alternaria alternata.
    Physiological and Molecular Plant Pathology (PMPP) 74: 100–110.
48. Chung, K.-R. 2009. Citrus diseases: ecology and control. Encyclopedia of Pest
    Management, 1:1, 1–5. CRC Press, Taylor & Francis. DOI: 10.1081/E-EPM-12004115
    (invited review)
49. Daub, M. E., and K.-R. Chung. 2009. Photoactivated perylenequinone toxins in
    plant pathogenesis. In: The Mycota Volume V – Plant Relationships, 2nd Ed.
    Spring-Verlag Press, Berlin Heidelberg, pp. 201–218. (Chapter 11)
50. Lin, C.-H., S. L. Yang and K.-R. Chung. 2009. The YAP1 homolog–mediated
    oxidative stress tolerance is crucial for pathogenicity of the necrotrophic
    fungus Alternaria alternata to citrus. Molecular Plant–Microbe Interactions
    (MPMI) 22: 942–952.
51. You, B.-J., M.-H. Lee, and K.-R. Chung. 2009. Gene-specific disruption in the
    filamentous fungus Cercospora nicotianae using a split marker approach. Archives
    of Microbiology 191 (7): 615–622.